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Covance
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Image Search Results
Journal: JAMA Oncology
Article Title: Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma
doi: 10.1001/jamaoncol.2022.5370
Figure Lengend Snippet: A, Kaplan-Meier plot comparing overall survival for patients with newly diagnosed glioblastoma treated with autologous tumor lysate-loaded dendritic cell vaccination (DCVax-L) and 1366 contemporaneous matched external control participants (ECPs) treated with standard of care, derived from 5 other contemporaneous matched randomized clinical trials. B, Cox hazard ratios of overall survival in prespecified subgroups of participants receiving DCVax-L or treated with standard of care in external trials. In the age subgroup, there were 50 participants in the DCVax-L group and 45 in the ECP group aged 65 years or greater and 182 and 184, respectively in the younger than 65 years group; in the residual disease subgroup, there were 86 patients in the DCVax-L group and 163 in the ECP group with significant residual disease and 146 and 210, respectively, with minimal residual disease; in the MGMT (O 6 -methylguanine-DNA methyltransferase) subgroup, there were 90 patients in the DCVax-L group and 199 in the ECP group with methylated MGMT and 131 and 349, respectively, with unmethylated MGMT. Subgroup analyses of survival, using the same parameters as the comparator publications, are presented with 95% confidence intervals to facilitate comparisons with the ECP.
Article Snippet: The
Techniques: Control, Derivative Assay, Clinical Proteomics, Methylation
Journal: Genes
Article Title: Prognostic Analysis of the IDH1 G105G (rs11554137) SNP in IDH-Wildtype Glioblastoma
doi: 10.3390/genes13081439
Figure Lengend Snippet: Pathological and molecular characteristics according to IDH1 G105G SNP status.
Article Snippet:
Techniques: Methylation
Journal: Genes
Article Title: Prognostic Analysis of the IDH1 G105G (rs11554137) SNP in IDH-Wildtype Glioblastoma
doi: 10.3390/genes13081439
Figure Lengend Snippet: PFS analysis of clinical/pathological/molecular features by Cox regression.
Article Snippet:
Techniques: Methylation
Journal: Genes
Article Title: Prognostic Analysis of the IDH1 G105G (rs11554137) SNP in IDH-Wildtype Glioblastoma
doi: 10.3390/genes13081439
Figure Lengend Snippet: DSS analysis of clinical/pathological/molecular features by Cox regression.
Article Snippet:
Techniques: Methylation